Chvostek's sign is the twitching of the facial muscles in response to tapping over the area of the facial nerve. Trousseau's sign is caused by carpopedal spasm as a result of inflating the blood-pressure cuff to a level above systolic pressure for 3 minutes. Both these signs are pathognomic for hypocalcemia. Low calcium levels lead to increased nerve excitability and thus, muscle spasms result. A common cause of hypocalcemia is hypoparathyroidism which often occurs due to iatrogenic removal of parathyroid glands during thyroidectomy. Autoimmune causes are also implicated.