Mishal Shanover 1 year ago

Types of von Willebrand Disease

Von Willebrand disease is the most common inherited disorder of bleeding. It occurs as a result of a qualitative or quantitative defect in von Willebrand factor. This factor is important not only for platelet adhesion and aggregation but also acts as a carrier protein for clotting factor VIII. While type 1 disease is the most commonly found subtype, others are relatively rare and have certain important differences which are highlighted in the image above. Treatment for most types except type 2B is by desmopressin. This drug enhances the release of vWF and promotes platelet activity. https://www.researchgate.net/publication/322196102_Inherited_bleeding_disorders/figures?lo=1&utm_source=google&utm_medium=organic