This amazing animation by Nucleus media is a great way to learn the basics of type 1 Diabetes Mellitus! This is an autoimmune condition in which our own immune cells attack the beta cells of pancreatic islets, thereby causing insulin deficiency. A decrease in insulin predisposes to hyperglycemia which can lead to severe microvascular and macrovascular complications. Patients may also land with diabetic ketoacidosis, a medical emergency.