Ahmadover 7 years ago
What is the effect of prolonged steroid therapy on eosinophils?
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over 7 years ago
Eosinophil adherence is transiently reduced following corticosteroid administration, eosinophil chemotaxis is inhibited by administration of corticosteroids, and the chemotaxis inhibiting effect is nontoxic, cell-directed, dose-dependent and reversible. Inhibition of eosinophil adherence and chemotaxis may in part explain how corticosteroids produce eosinopenia and decrease the local accumulation of eosinophils.
