Mishal Shanabout 4 years ago

Myelofibrosis

Myelofibrosis is a condition leading to obliteration of bone marrow by fibrous tissue. Often associated with mutations in the JAK-signaling pathway, it leads to marrow failure, peripheral cytopenia and excessive extramedullary hematopoiesis. Learn about the pathogenesis and key features in the image above. Source: https://www.sciencedirect.com/science/article/pii/S0268960X20300412#f0010