Hemochromatosis

Hemochromatosis is an genetic disorder that is inherited in an autosomal recessive form and results in accumulation of iron in abnormal amounts in the parenchyma of different organs resulting in pathology within those organs. The organs commonly involved include: - Liver (hepatomegaly, cirrhosis) - Skin (bronzing or hyperpigmentation) - Pancreas (diabetes mellitus) - Joints (arthropathy) - Gonads (amenorrhea, impotence, hypogonadism) - Heart (cardiomyopathy) - Bones (osteopenia and osteoporosis) - Hair loss and koilonychia in nails Image Source: https://www.shutterstock.com/image-vector/iron-overload-healthy-liver-hemochromatosis-hepatology-1892848840