Pulmonary edema is caused by cardiogenic and non-cardiogenic causes. It develops and presents as sudden onset dyspnea, orthopnea, cough and edema. In pulmonary edema there is sudden onset of fluid accumulation which results in disruption of air exchange. The pathophysiology in cardiac and non-cardiac causes varies. In cardiogenic causes increased pulmonary capillary pressure occurs due to left ventricular failure. While in non-cardiac causes the cause is injury to lung parenchyma occurs. The non-cardiac causes of acute pulmonary edema include: negative ionotropic medication, fluid over load, high output cardiac failure, anemia, thyrotoxicosis, sepsis, ARDS, pneumonia, trauma, toxins, non-compliance with medication and renal artery stenosis.