Nociceptive pain Nociceptive pain is a type of pain caused by damage to body tissue. People often describe it as being a sharp, achy, or throbbing pain. It’s often caused by an external injury. For example, if you hit your elbow, stub your toe, twist your ankle, or fall and scrape up your knee, you may feel nociceptive pain. This type of pain is often experienced in the joints, muscles, skin, tendons, and bones. It can be both acute and chronic