Maryum Mehboobover 3 years ago

Hutchinson-Gilford syndrome or Progeria

Hutchinson-Gilford syndrome or Progeria is a unique autosomal dominant genetic disorder that cause early aging in the children. The LMNA gene that encodes for the Prelamin A is mutated. Symptoms include retarded growth, large head and eyes, small jaw, beak tipped nose, high-pitched voice, hair loss and wrinkled skin. These children have an average life span of 13 years with most deaths occurring due to heart problems.