Prednisolone Oral and Prednisone Oral are slightly different but have same functions. Prednisone Oral is converted into Prednisolone Oral by liver enzymes. This drug also belongs to the class of Corticosteroids. Prednisolone Oral is an important medicine for a wide range of diseases. This prescription medicine is used for the treatment of respiratory diseases, dermatologic diseases, collagen diseases, hematologic diseases, allergy-associated conditions, ophthalmic diseases, gastrointestinal diseases, endocrine disorders and neurologic disorders. The side effects of Prednisolone Oral include - Menstrual irregularity - Acne - Headache - Hypertension - Facial flushing - Fragile skin - Trouble sleeping - Distention of abdomen - Muscle weakness - Glaucoma and bulging of eyes - Fluid retention - Weight gain - Vertigo - Diabetes - Delayed wound healing Prednisolone Oral interacts with the following drugs. - Immune-suppressants e.g. Azathioprine, Cyclosporine - Anti-progestational Steroids e.g. Mifepristone - Anti-platelet Drugs e.g. Clopidogrel - NSAIDs e.g. Ibuprofen, Celecoxib