Javid Misbaabout 7 years ago

Medical pearl 03 ECG Abnormalities associated with Hypothyroidism Severe hypothyroidism (myxoedema) causes a *triad of: *Bradycardia *Low QRS voltage *Widespread T-wave inversions (usually without ST deviation) Other ECG changes that may be seen include: *QT prolongation *First degree AV block *Interventricular conduction delay #Mechanism:- ECG changes may be secondary to: *Myxoedematous deposits of gelatinous connective tissue within the myocardium. *Decreased activity of the sympathetic nervous system *Effects on the myocardium of reduced levels of thyroxine (i.e. reduced inotropy/chronotropy)