Dustin

in Articles

The RAS has two basic "arms" of action that counterbalance each other. The ACE/angiotensin II/AT1 receptor axis promotes coagulation, inflammation, fibrosis, and insulin resistance. The ACE2/angiotensin1-7/Mas receptor/AT2 receptor axis does largely the opposite: anti-inflammatory, anticoagulant, and so on. Both original SARS and SARS-CoV-2 use “ACE2 to hitchhike inside cells, then they highjack cellular machinery for viral replication and halt cellular expression of ACE2. Without the ACE2 counterbalance, the destructive potential of unchecked ACE/angiotensin II/AT1 is unleashed” an interesting perspective

Could RAS Dysfunction Explain COVID's Effects?

Could RAS Dysfunction Explain COVID's Effects?

Dr Andrew Wilner speaks with the researcher proposing that the renin-angiotensin system is the reason for COVID-19's complex symptoms.

#COVID-19 #RAS #THEORY #MEDICAL

Comments

Login to add a comment