Liver Disease and Hemostasis Disorders. Liver Disease can lead to bleeding, thrombosis, or both (AICF) Vitamin K Deficiency | Hemorrhagic Disease of the Newborn or Vitamin K dependent bleeding (VKDB) is a bleeding disorder that occurs due to deficiency of vitamin K. Factor XIII Deficiency | Fibrin Stabilizing Factor Defect. Factor X Deficiency is an autosomal recessive disease. In factor X deficiency, there is a coagulation (secondary Hemostasis) defect. In a previous video: we discussed "hemophilia A, Hemophilia B, and Hemophilia C | A Comparison." Hemophilia is a genetic Coagulation Disorder characterized by abnormally excessive bleeding 🩸 even after a minor scratch. Hemophilia is divided into three subtypes: hemophilia A, hemophilia B, and hemophilia C. Hemophilia A and hemophilia B are X-linked recessive, whereas hemophilia C is autosomal recessive.'