Von Willebrand Disease (VWD) | The Most COMPREHENSIVE Explanation!
Von-Willebrand factor (vWF) comes from the meagakaryocytes (bone marrow) as well as the Weibel-Palade bodies (endothelial cells). Von Willebrand factor (vWF) helps the platelets adhere to the sub endothelial collagen via GP1b receptor on the platelet. Von Willebrand disease (vWD) is the most common inherited bleeding disorder worldwide. Primary hemostasis involves forming a platelet plug (thrombocytes) whereas secondary hemostasis involves making a fibrin thrombus (coagulation factors). Ionized calcium helps blood coagulate. We test for primary hemostasis via platelet count, bleeding time, and platelet aggregometry. We test secondary Hemostasis via prothrombin time (PT), activated partial thromboplastin time (aPTT), and the old coagulation time (or clotting time, or thrombin time). Von Willebrand Dusease (vWD) affects primary as well as secondary Hemostasis. Hemolytic Uremic Syndrome (HUS), atypical Hemolytic Uremic Syndrome (aHUS), and Thrombotic Thrombocytopenic Syndrome (TTP). Atypical hemolytic uremic syndrome (aHUS) is similar to thrombotic thrombocytopenic Purpura (TTP). Typical Hemolytic Uremic Syndrome (HUS) is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. Thrombotic thrombocytopenic purpura (TTP) is a pentad of microangiopathic hemolytic anemia, thrombocytopenia, acute renal failure, fever, and neurological abnormalities.
Their bodies cannot excrete wether in urine stools etc certain kinds of proteins
Dysmorhea heavy menstrual periods prescribing nothing but usually they birth control pills too stop bleeding periods may be painful along with other areas of this condition is a dnc to clean out womb and if it doesn't stop or subside the bleeding then either a total or partial hysterectomy is needed and horomones