Topic---Derivatives of monosaccharides and clinical correlation.
♦️Derivatives of monosaccharides:♦️ ▪️-when reducing agents convert monosaccharides into corresponding alcohols as given below . *D-Glucose -. -D-sorbitol *D-fructose ------D-sorbitol and D- mannitol *D-Ribose _-------D -Ribitol *D-Mannose-------D-Mannitol *D-Galactose-----D-Dulcitol . ♦️ Clinical correlation 👩⚕️♦️ ▪️Ribitol is a constituent of riboflavin and flavin coenzymes. ▪️ Sorbitol and dulcitol when accumulated produce pathological changes in tissues (CATARACT OF LENS , PERIPHERAL NEUROPATHY , NEPHROPATHY ) . --These changes are usually associated with the sever form of DIABETES MELLITUS. ▪️ Sorbitol, mannitol and dulcitol are used to identify bacterial colonies as these molecules are used as energy sources for bacteria. ▪️ Mannitol ---it is also used to reduce raised intracranial pressure.
