Status Asthmaticus :- ( Key Words ) Severe attack of brochial asthma with bronchial obstruction ( From Beginning Or During Course Of The Episode ) . Causes :- • Exposure To Allergens • Infections • Psychogenic Stress • Inadequate Therapy • Excessive Use Of Aesol • Inappropriate Use Of Tranquilizers • Respiratory Depression Pathogenesis :- • Bronchospasm Exaggerated • Narrowing Of Bronchial Lumen ( Excessive Mucus - Inflammatory Oedema Of Bronchial Mucosa - BM of Mucosa Thickened And Hypertrophy Of Smooth Muscle Of Bronchi ) • Increased Viscosity Of Mucus ( Dehydration ) • Ventilation-Perfusion Mismatch • Plugging Of Airways ( Mucus, Eosinophils, Desquamated Epithelial Cells And Charcot Leyden Crystals ) • Atelectasis ( Obstruction ) - Lungs Remain Hyperinflated. Clinical Features, Laboratory Findings And Management - Next Post
