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MEDizzy
Ozgur Koyuncu
Ozgur Koyuncu over 5 years ago
Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD

Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD

Chen, Deister et al. show that Shank3B-knockout mice display hypersensitivity to tactile sensory stimulation and that dysfunction of interneurons in somatosensory cortex contributes to the sensory hyper-reactivity in this mouse model of autism.

Source: https://www.nature.com/articles/s41593-020-0598-6
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