Thrombocytosis (thrombocythemia) is increased platelet count. Thrombocytopenia is decreased platelet count. Normal platelet count is 150,000 to 400,000/ microliter. Platelet count test is commonly ordered as part of the complete blood count (CBC). Secondary thrombocytosis is secondary to another disease (e.g. infection or inflammation). Hemostasis is defined as “cessation of blood bleeding”. There are 2 types of hemostasis: 1. Primary hemostasis: formation of weak, temporary platelet plug (by platelets). 2. Secondary hemostasis: formation of stronger fibrin meshwork (by coagulation factors).