Ichthyosis Congenital
Icthyosis congenital is a severe genetic disorder that mainly affects the skin. The newborn infant is covered with plates of thick skin that crack and split apart. The thick plates can pull at and distort facial features and can restrict breathing and eating. Mutations in the ABCA12 gene causes it. The baby was the fourth outcome of a consanguineous marriage, the couple being maternal first cousins. The parents did not report any history of repeated miscarriages/stillbirths, genetic anomalies in the elder children, or any inherited skin disorders. It was an unbooked case.
The consanguineous marriage has nothing to do with this, the autosomal recessive type of transmission of this gene does make it more likely to occur if both parents have the ABCA12 gene present, but could easily occur in other non-blood related relatives as well. Due to my beliefs I do not support in any way the consanguineous marriage, but leave your personal beliefs outside the platform for the sake of better good, to learn something.
Consanguinity is the leading cause for expression of recessive genes. Only rare people like.... will test for ABCA12 gene and marry 🤦♂️. Dont underestimate consanguinity.
Yes it can occur anywhere any time... But probability of getting it is way too high if it runs with same family tree..
Some people need to know that consanguinity has close genetic relationship # derek
