An otherwise healthy 58-year-old man was referred for the management of painful swelling on the left side of his tongue. A lesion had been growing insidiously for the preceding 8 months, with no sign of bleeding. The patient had been smoking more than 20 cigarettes a day for 26 years. Examination of the oral cavity revealed a vegetative circular mass on the left side of the tongue (measuring 2 cm in diameter) and associated leukoplakia. A biopsy was performed, and histopathological examination revealed squamous-cell carcinoma. The tumor was surgically removed, and the tongue was reconstructed with the use of a free flap of tissue. No adjuvant therapies were administered. There were no signs of recurrence after 36 months of follow-up.