The ACE INHIBITORS causes the "DRY COUGH" but what is mechanism that it cause dry cough as side effect
Ace inhibitors prevent inactivation of bradykinin resulting in its accumulation which causes irritation to respiratory mucosa leading to dry cough
ACE degrades bradykinin. inhibition of bradykinin degradation leads to dry cough
Inhibit degradation of bradikinin results it's accumulation in the body. Inflammatory response