MEDizzy
MEDizzy
Pratipalsinh vaghela
Pratipalsinh vaghelaover 5 years ago

Give the mechanism

The ACE INHIBITORS causes the "DRY COUGH" but what is mechanism that it cause dry cough as side effect

4
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over 5 years ago

As far as I know it is bradykinin release that causes it

over 5 years ago

Ace inhibitors prevent inactivation of bradykinin resulting in its accumulation which causes irritation to respiratory mucosa leading to dry cough

over 5 years ago

ACE degrades bradykinin. inhibition of bradykinin degradation leads to dry cough

over 5 years ago

Inhibit degradation of bradikinin results it's accumulation in the body. Inflammatory response

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