AshleyCooper10 months ago

D-dimer

D-dimer is the end result of the degradation of the stabilized fibrin fibers. Plasminogen is converted to plasmin, thanks to tPA/urokinase...Plasmin will degrade the fibrinogen into fibrinogen degradation products, the fibrin into fibrin degradation products, and the stabilized fibrin into d-dimer. D-dimer is a subset of fibrin degradation products (FDPs). Plasma level of D-dimer is elevated in cases of DIC, DVT, coronary thrombus,...etc. The presence of high plasma levels of d-dimer proves that there were some stabilized fibrin fibers in the plasma.