Figure illustrates the three possible enhancement kinetic curves in breast MR Imaging (can also applied to other organs such as prostate), after the administration of Gadolinium-based contrast agent (GBCA).
a) Curve type 1: progressive enhancement pattern
• Typically shows a continuous increase in signal intensity throughout time.
• Usually considered benign with only a small proportion of (5-10%) of malignant lesions having this pattern.
b) Curve type 2: plateau pattern
• Initial uptake (slow or fast) followed by plateau phase towards the delayed phases of the dynamic study.
• Suspected for malignancy.
c) Curve type 3: washout pattern
• Has a relatively fast uptake (wash-in) and shows reduction in enhancement (wash-out) towards the delayed phases of the dynamic study.
• Considered strongly suggestive of malignancy.
Images courtesy of Christos Tsiotsios.