The combination of F-18 choline PET and multiparametric MRI (mpMRI) shows promise for detecting prostate cancer, according to a study in the July issue of the Journal of Nuclear Medicine. T2-weighted fast spin-echo MRI (A), F-18 choline PET (B), and fused PET/MRI (C) show a 0.68-cm3 left anterior transitional zone lesion that was confirmed on targeted biopsy. A magnified view of PET/MRI (D) shows a target lesion (magenta) and respective mirrored (blue) background volumes of interest. Image courtesy of JNM.