Simultaneous Multi-Slice (SMS) speeds up imaging significantly through the simultaneous excitation and readout of multiple slices. Together, Simultaneous Multi-Slice Diffusion and BOLD bring advanced neuro applications into clinical routine – offering various advantages. For diffusion-weighted imaging, slice acceleration can be used to reduce scan time and/or achieve higher spatial/diffusion resolution. For BOLD, slice acceleration can be used to increase temporal sampling of BOLD data, for higher sensitivity to BOLD signal changes, and/or to increase slice coverage/resolution.