Diffusion MRI (or dMRI) is a MRI method which came into existence in 1985. It allows the mapping of the diffusion process of water molecules in biological tissues, in vivo and non-invasively. Molecular diffusion in tissues is not free, but reflects interactions with many obstacles, such as macromolecules, fibers, and membranes. Water molecule diffusion patterns can therefore reveal microscopic details about tissue architecture, either normal or in a diseased state. Table provides information about the different diffusion models.