Liver tumor
A 41-year-old, previously healthy woman has noted abdominal discomfort for the past month. Laboratory studies show normal serum total protein, albumin, AST, ALT, and bilirubin, but her alkaline phosphatase level is elevated. Serologic testing for hepatitis A, B, and C viruses is negative. Abdominal CT scan shows a 9-cm right hepatic lobe mass with irregular borders. The lesion is resected, and gross inspection reveals a central stellate scar with radiating fibrous septa that merge into surrounding hepatic parenchyma. On microscopic examination, the mass has prominent arteries in dense connective tissue along with lymphocytic infiltrates and bile duct proliferation. What is the most likely diagnosis? A. Cholangiocarcinoma B. Focal nodular hyperplasia C. Hepatic adenoma D. Hepatocellular carcinoma E. Macronodular cirrhosis F. Metastatic adenocarcinoma #usmle #usmlestep1 #medicine —�—�— . . Answer: Focal nodular hyperplasia (FNH) is a benign tumor of the liver (hepatic tumor), which is the second most prevalent tumor of the liver (the first is hepatic hemangioma). It is usually asymptomatic, rarely grows or bleeds, and has no malignant potential. . Gross findings: 🌟1). Poorly encapsulated nodule, 🌟2). Central depressed stellate scar, 🌟3). Fibrous septae radiating to the periphery.
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