Dr.Sanaalmost 7 years ago

LIPODERMATOSCLEROSIS

Lipodermatosclerosis is a skin and connective tissue disease and occurs in patients with venous insufficiency...... It is a form of lower extremity panniculitis(an inflammation of subcutaneous adipose tissue) Increased blood pressure in the veins (venous hypertension) can cause diffusion of substances, including fibrin, out of capillaries. Fibrotic tissue may predispose the tissue to ulceration. Recurrent ulceration and fat necrosis is associated with lipodermatosclerosis. In advanced lipodermatosclerosis the proximal leg swells from chronic venous obstruction and the lower leg shrinks from chronic ulceration and fat necrosis resulting in the inverted coke bottle appearance of the lower leg.