some common causes of an enlarged spleen: Infections Viral infections, such as mononucleosis Parasitic infections, such as toxoplasmosis Bacterial infections, such as endocarditis (an infection of your heart's valves) Cancer Leukemia, a cancer in which white blood cells displace normal blood cells Lymphoma, a cancer of lymph tissue, such as Hodgkin's disease Other causes of an enlarged spleen include: Inflammatory diseases such as sarcoidosis, lupus, and rheumatoid arthritis Trauma, such as an injury during contact sports Cancer that has spread (metastasized) to the spleen A cyst, a noncancerous fluid-filled sac A large abscess, a pus-filled cavity usually caused by a bacterial infection Infiltrative diseases such as Gaucher's disease, amyloidosis, or glycogen storage diseases
Every disease commented by our doc friends is crct answer only as all of them are good causes of splenomegaly
Chronic myeloid leukemia ,Myelofibrosis, Gaucher disease ,Lymphoma, kalaazar