Hello doctors.. help me with this ....how do we know the difference between Dextro and Levo in Haworth projection ??
The chiral carbon furthest from the carbonyl group determines the absolute configuration L or D of the sugar. If in the fischer projection, the OH group on the chiral carbon furthest from the carbonyl is pointing left, then it's L. If it's pointing right, then it's D. Note: L and D are enantiomers, not epimers. So, every chiral carbon center inverts. It's just that you assign L and D based on the chiral carbon furthest from the carbonyl.