Which amino acid (s) are important in inducing insulin secretion from islets of Langerhans? A.glycine B.arginine C.leucine D.tryptophan E.lysine
In the 1980s, Sener and Malaisse showed that leucine stimulates insulin secretion by allosterically stimulating glutamate dehydrogenase (GDH) activity.Â
The mechanism for inducing of insulin secretion by amino acid (BRIN-BD11 cells) still is under research.