MEDizzy
MEDizzy
Bibhu Prasad Sahu
Bibhu Prasad Sahualmost 5 years ago
Cutaneous Mastocytosis

Cutaneous Mastocytosis

Cutaneous mastocytosis is a form of mastocytosis that primarily affects the skin. There are three main forms of the condition: maculopapular cutaneous mastocytosis (also called urticaria pigmentosa), solitary cutaneous mastocytoma, and diffuse cutaneous mastocytosis. There is also an exteremely rare form called telangiectasia macularis eruptiva perstans. The signs, symptoms and severity of the condition vary by subtype. Most cases of cutaneous mastocytosis are caused by changes (mutations) in the KITgene. This gene encodes a protein that helps control many important cellular processes such as cell growth and division; survival; and movement. This protein is also important for the development of certain types of cells, including mast cells (immune cells that are important for the inflammatory response). Certain mutations in the KIT gene can leads to an overproduction of mast cells. In cutaneous mastocytosis, excess mast cells accumulate in the skin, leading to the many signs and symptoms of the condition.

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Top rated comment
almost 5 years ago

Is this completely curable doc?

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